Proteoglycans for the skin, reviews, and properties

The proteoglycans are molecules made of proteins and sulfates that have various functions in the skin and cartilage of the human body. Since their composition can vary due to the large number of proteins that exist, so do their utility and molecular size. This makes them effective for dehydrated skin by providing moisture, reactivating collagen formation, and also as a treatment for joints.

There are different types of proteoglycans, but the most well-known is hyaluronic acid, the only one without sulfate, also known as a polysaccharide. Others, with sulfated formulations, include chondroitin, heparan sulfate, keratan, and others that can have various benefits for beauty and aesthetic treatments, such as ampoules with vitamin C that revitalize the skin.

Properties of proteoglycans

As you can imagine, some proteoglycans have properties very similar to hyaluronic acid since certain products are formulated based on this substance. They are widely used in cosmetics that can be purchased in ampoules, and their appearance is similar to a gel or serum. It is somewhat transparent and oily, although not greasy at all. When you apply a proteoglycan, you immediately notice that the skin absorbs it easily and effectively, leaving no greasy residue or sticky effects. So its appearance is just that. It is a cosmetic in gel form packaged in a small ampoule.

Another property of proteoglycans is that they spread well over the face. A small amount covers a large surface area. The same happens with serum. So if you have tried one and liked it, its use will feel very familiar.

In reality, proteoglycans are glycoproteins that, depending on molecular bonding, can have applications for repairing dehydrated skin, improving collagen formation, and enhancing vitamin C for the face. But they also, when combined with certain types of sulfate, provide consistency and balance to the synovial fluid in the joints. Additionally, they have important applications in the vitreous humor, the fluid in the eyes, and the moisture in the mouth since these contain a high percentage of glycoproteins. You can easily find them in stores for various uses, such as skin care, improving gum recovery, alleviating dry eye symptoms, and even in trauma treatments. So let’s look at the most common applications.

For the skin

Proteoglycans in ampoules

People who benefit the most from all their effects are those with dry skin, for example, after sun exposure, after summer, or as they age. It works for both women and men, making it great since a box of ampoules can be used by both.

It plays a role in the extracellular matrix, occupying the space between cells. It creates the ideal environment for cellular tissues to stay comfortable and maintain all necessary moisture. Additionally, it functions as a transmission channel for essential nutrients needed for dermis and epidermis nourishment.

In the skin, they form large groups of hyaluronans and fibers like collagen. So maintaining good levels of proteoglycans is essential for keeping the skin firm and plump, preventing aging with hyaluronic acid for the skin.

Proteoglycans SPF

Proteoglycans SPF is a formulation that includes a sun filter in the ampoules used for treatment. In addition to promoting the reconstruction of dehydrated skin tissues, they also help to some extent in preventing UVA and UVB rays from damaging cells and breaking down molecules during the treatment. Some contain vitamin C to enhance the antioxidant effect, which is so important for the face.

For the joints

In this formulation, the most well-known is hyaluronic acid for the knee, injections for the hip, elbow, and joints affected by injuries and degenerative cartilage diseases. It can be used when there has been synovial fluid leakage and to restore synovial levels that prevent friction and joint pain. There are excellent treatments that must be applied by specialist doctors through injections or as a supplement with chondroitin, but they are truly worth it. You just have to look at the opinions of countless patients. However, not everyone should undergo these treatments.

How to use them

How to use proteoglycans

It is really very simple, and we will focus only on the use of proteoglycans for the skin since other applications are for professionals.

To apply them, you must first clean your skin. With a clean face, simply take an ampoule and break the top part. Pour a small amount onto your fingertip or the palm of your hand to prevent any content from being lost. Most commonly, the box includes an applicator along with the ampoules, making it much easier and more convenient.

Then, you just need to apply with a gentle massage on your face, just as you would with your regular moisturizer. Remember that you only need a small amount, as it absorbs very well and spreads widely.

Price of proteoglycans

Here, we will also focus on those for cosmetic use since, in other cases, it is best to seek specialized advice.

Depending on the brand, you will find different prices for proteoglycans. These range from $18 to $32 approximately. Depending on the store where you buy them, you may find significant price variations. The most well-known brands are Martiderm proteoglycans, Endocare, and Mesoestetic. All three focus heavily on products that improve skin health and quality. So you can fully trust these types of cosmetics, which revitalize epidermal tissues. However, there are also other brands with good results. It all depends on finding what best suits your skin condition and budget.

Reviews on the use of proteoglycans

Depending on the level of skin dehydration, you may notice their effects in just one day or need some time to see a plumper and fuller appearance. Packs containing 30 ampoules last for one month if you use one ampoule daily, morning and night, or two months if you use only half an ampoule per day. So within this period, you will really see their effects.

Ideally, they should be used as an intensive treatment to combat certain symptoms of dehydration and dryness, for example, after summer, in winter if you are exposed to the cold, as it damages the skin, or when you notice a loss of natural glow and less elasticity in your face.

The most visible effect is that the skin stops being dry. It hydrates, moisturizes, and improves tone. It enhances luminosity and prevents facial aging by improving signs of aging. Proteoglycans SPF also provide extra protection against sun rays to further prevent dehydration, improve skin firmness, and promote a younger and healthier appearance. They can be used at any age, from 20 to 60.

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11 Responses

  1. Ana Amalia says:

    Argentine laboratory brands where I can find it?

    • Ana Amalia says:

      The brands mentioned are sold in Argentina, how much do they cost in Argentine pesos? I would appreciate a quick response. Thank you.

    • Marta Lerinde says:

      You can look for Argentine laboratories selling the product in pharmacies or health stores. Some brands may be available online. The price depends on each brand, you will find both cheap and expensive options.

  2. ximena morales says:

    Is it sold in Chile?

    • Marta Lerinde says:

      For Chile, you can check pharmacies and dermatological product stores. You can also search on online platforms that offer shipping.

  3. Amaya says:

    Is it good to apply the ampoule in the morning and at night?

    • Marta Lerinde says:

      It depends on the type of ampoule. Some are designed to be used only in the morning or at night. Check the manufacturer’s instructions for proper use.

  4. rosa maria bravo says:

    I live in Chile. I ordered proteoglycans, and in Chile, the institute that tests cosmetics rejected it, and they didn’t give me any explanation. I’m outraged.

    • Marta Lerinde says:

      It’s a frustrating situation. It could be due to specific health regulations in Chile. I recommend contacting the regulatory institute to find out the exact reason for the rejection.

  5. yamilet says:

    What would be good for facial spots?

    • Marta Lerinde says:

      For facial spots, you can try products with glycolic acid, vitamin C, or niacinamide. We’ve posted about all of them, just type each active ingredient into our search engine, or on Google searching for example “mismumi.com vitamin C” or “mismumi.com glycolic acid.”
      Daily use of sunscreen is also important to prevent the spots from darkening further.