Arginine is an essential amino acid well known under its chemical forms called “L-arginine” or “D-arginine”. It is necessary to take it because the body cannot synthesize some nutrients by itself. So to keep its levels regulated and avoid deficiencies, we have to take it through food with a rich and varied diet or also through the intake of supplements based on capsules or tablets.
It belongs to the group of 20 essential amino acids present in human beings. It can transform and take the dextrorotatory form, which is designated with a “D” before its name, or the levorotatory form, which places the letter “L” before it.
Although the two are very similar, some properties of L-arginine differ according to their chemical formulation. This is the most beneficial for human health, so we will focus on it.
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L-arginine Properties
There are different reasons why you should follow a varied and healthy diet, but one of them is to maintain a constant supply of amino acids for your body. Your health, vitality, and preserving youth for longer depend on it.
There are several, but we highlight that the properties of L-arginine serve to improve the immune system, increase defenses, and establish proper functioning of the urea cycle, through which the body gets rid of ammonia, which is highly toxic. In addition, it improves blood circulation, establishing a better body fat percentage balance.
But not only that.
It has many other benefits of arginine and is used because it has many qualities such as those indicated below:

- Increases the number of leukocytes.
- Creatine synthesis.
- Urea production.
- Participates in the creation of nitric oxide.
- Improves the circulatory system.
- Reduces the amount of adipose tissue.
- Stabilizes blood pressure.
- Stimulates growth hormone and favors cellular regeneration.
- Improves rehabilitation time and recovery from wounds and tears.
- Increases muscle mass.
- Amplifies insulin sensitivity.
- Stimulates male erection.
What it is used for
It is widely used by athletes because by improving ammonia elimination, it facilitates muscle recovery. One of the functions of L-arginine is to promote the creation of nitric oxide and act in toxin expulsion.
It is also used in patients who have an immune deficiency. It helps in the processes of creating the leukocyte colony, and this makes you more prepared to fight attacks from viruses and bacteria.
As it is involved in creatine synthesis, it is very important for muscles, muscle growth, and proper rest. In this sense, it can be used to stimulate the increase of muscle mass in fitness and bodybuilding. Because it produces an increase in HGH or somatropin, it is key to generate progression and a constant increase of muscle fibers.

The elevation of somatropin and growth hormone is fundamental so that the tissues of the body are repaired. Without it, at the end of the day all the wear you experience would continue to accumulate, and in a matter of days you would become ill.
It is a powerful vasodilator and works well for some cases of erectile dysfunction and cardiovascular diseases.
To answer what arginine is used for, we can say that it is used to treat heart diseases, improve blood pressure, and stimulate blood circulation. In addition, as it intervenes in several metabolic processes, it is key in the absorption and elimination of adipose cells and fatty material from the human body. So it is used for weight loss and to level blood cholesterol.
Side effects
Because amino acids have a key role in protein formation, they are necessary for all processes of the body. In this aspect, they can also be used as a supplement for athletes and are even used to treat people with diseases. Some of them need to enhance certain areas of the functioning of the human body, and that is where this amino acid acts in its different chemical forms.
When L-arginine is taken through food intake, there is no risk of suffering side effects, neither in the short nor long term. On the other hand, when it is used through arginine capsules, injections, and other types of supplements, there may be some risk to health and adverse reactions. We are going to describe the most common side effects:
- Stomach pain.
- Inflammation.
- Diarrhea.
- Difficulty breathing.
- Low blood pressure.
- Gout.
Although some symptoms are mild and temporary, others can trigger serious conditions. So it is always necessary to follow the indications of a health professional in its different fields.
People who have diseases may see the symptoms they suffer altered. Some include increased asthma, blood abnormalities, allergies, and changes in intestinal function.
Contraindications
- Pregnancy.
- Breastfeeding.
- Children.
- Asthma and respiratory problems.
- Cirrhosis.
- Herpes.
- Low blood pressure.
- Heart problems.
- Kidney failure and kidney diseases.
In general, it is considered a very safe amino acid, but there are people who must be extremely cautious in its use. Whenever there is a medical condition, it is necessary to consult a doctor because interactions may exist with medications and herbal preparations, enhancing or reducing their effects, as well as intervening in healing processes. There are cases in which administering arginine by injection can be very beneficial, and others in which taking a couple of capsules can worsen a disease or infection.
Whenever you use amino acids, it is recommended that you follow the guidelines for use and intake indicated by a nutritionist or medical specialist. It is also important to stop taking this supplement 2 weeks before undergoing any type of surgery.
Using arginine and ornithine

The combination of these two amino acids results in a special effect. Ornithine is an essential amino acid, as is arginine. Both are related to the elimination of ammonia in the human body, detoxification of the body, and toxin expulsion.
Taking ornithine and arginine works as a diuretic. It promotes the reduction of fatigue. This makes it common to see it used in certain sports disciplines such as fitness, weight training, and activities aimed at achieving better athletic performance.
These two amino acids are also used together with a high-protein diet to increase muscle mass. Their goal is to achieve increased training endurance with more favorable recovery.
It is recommended to take L-arginine and L-ornithine in a 2×1 ratio.
Because both substances intervene in the formation of growth hormone, when taken together they are considered anabolic, or at least serve the same purposes.
The sports in which they are usually used include cycling, bodybuilding, swimming, and all those in which endurance or muscle power allows athletes to surpass personal performance goals.
Arginine with ibuprofen
It is used to relieve headaches and reduce mild inflammation. Arginine with ibuprofen can be used with other drugs or as a dietary supplement. When used with ibuprofen, it is classified as a medication, so it must be purchased at a pharmacy, where different brands and generic versions are available. This is not the case when it is L-arginine as a dietary product. In this case, no prescription is required, and it can be purchased in specialized stores.
Taking Arginine, Ornithine, and Lysine at the same time

The use of these three essential amino acids has an anabolic function. They improve the processes of growth hormone production and creatine formation. Combined with the effects of arginine, ornithine, and lysine in improving toxin elimination and converting fatty acids into energy, they form a combination of amino acids with an important role in sports performance.
They improve HGH levels and insulin production. In people who practice bodybuilding and muscle hypertrophy, increases have been detected in different studies. Adding lysine to ornithine and arginine enhances these effects.
Recommended dose
There are different recommended daily amounts depending on the benefits you want to achieve when taking L-arginine. The dose ranges from 4 g to 20 g daily. People with medical conditions may need the administration of a certain amount several times a day, two or three times, until completing the stipulated intake to improve their deficiency.
In the case of men who use L-arginine to combat erection problems, the dose is lower, around 5 grams daily.
Likewise, people who use it as a bodybuilding supplement should take between 4 and 5 g per day.
In all cases, you must follow the indications of a specialist, read the usage guidelines, and follow the instructions.
It must be taken into account that when taking concentrated arginine, the amount is much greater than through other simple, non-concentrated means and in small proportions. Exceeding the maximum recommended dose can produce side effects and unwanted reactions.
How to use arginine
People who have to take it under medical prescription must follow the regimen indicated by the doctor. This is obvious, but frequent doubts about how to take arginine arise when the use is recreational or for sports purposes. So we are going to explain when the best time is for you to absorb it and for it to have effects and beneficial properties aimed at increasing muscle size.
If you are looking for results to improve musculature and training, you should take arginine between 30 and 60 minutes before going to the gym to train. This gives your body time to metabolize the dose you have taken and prepares the muscles and the circulatory system to deliver the entire stream of necessary nutrients. As nitric oxide levels increase, there will be greater blood flow to the muscles, which entails more oxygen and more fuel to perform exercises.
If you seek to enhance recovery instead of taking it before training, you should take arginine just before going to sleep.
Do you want quality arginine?
It is no secret that certain laboratories work better than others, have more rigor, and market dietary supplements in very good conditions. In addition, an important fact is that all this is done while maintaining an adequate profit margin without exceeding certain limits. This makes these brands ideal because it facilitates access for anyone. So if you are interested in knowing more about where to buy arginine inexpensive and high quality, you just have to take a look.

I suffer from hypertension and fluid retention. I used to take Valsartan, but it caused allergic effects and I stopped taking it. Instead, I take arginine 500 mg or 1000 mg in the morning and it works well for me, but I need to take something to eliminate fluid retention because my legs swell. My question is: can I take dandelion together with arginine, or is there any contraindication? Thank you. Sincerely, best regards.
I am 57 years old. Can I take it? I lack muscle mass, and for how long can I take it?
I want to know if taking arginine can harm me with the osteoarthritis I suffer from. I appreciate your response.
That’s good, I have bought arginine 500 mg and ginseng. Will it help me with erectile dysfunction?
Hello, I am eighty-two years old and I take medication for blood pressure (Renitec 10) twice a day, and Nivas for dizziness twice a day, and I am thinking of taking five grams per day of L-arginine. Is it advisable for me at my age?