Glucosamine is a natural substance produced by the human body. It is part of the synovial fluid that protects the joints, bones, and cartilage. It is also found in vertebrate animals and in the shells of crustaceans and shellfish, from which it can be extracted to make supplements for joint and bone care. Glucosamine sulfate often comes from marine sources to produce powder and capsule forms, although it can also be synthesized in a laboratory.
What are the properties of glucosamine used for?
It is commonly used to treat degenerative cartilage diseases such as arthritis, osteoarthritis, osteoporosis, and all types of injuries where there is damage to the knees, elbows, and other joints like the fingers of the hands.
The properties of glucosamine are widely used for osteoarthritis, the type of arthritis that affects the most people. It also helps to treat osteoarthritis.
Glucosamine is a precursor to proteins and lipids, which improves the production of collagen in the body. This is very beneficial since cartilage is largely made up of this protein.
It also forms part of the synovial fluid found in the knee cavity and protects all joints during movement. It provides benefits for the hips and spine, as these have a strong joint component.
- Anti-inflammatory
- Pain-relieving
- Regenerative of cartilage
People with osteoarthritis are often recommended by specialists to add a glucosamine supplement in capsule form to improve painful symptoms and prevent further cartilage wear. In this regard, it can alleviate pain and make life easier for people suffering from cartilage wear in the knees, hips, elbows, shoulders, etc. It is also helpful for those with degeneration and deformation, as in osteoarthritis.
The recommendations made by orthopedists and healthcare professionals focus on the anti-inflammatory and pain-relieving properties for the joints. When taking glucosamine, discomfort from worn cartilage can be reduced. Therefore, in many cases, it helps people with joint damage to engage in activities they couldn’t do before due to pain and stiffness.
How long should glucosamine be taken to notice effects?
It is a supplement that takes effect in the medium and long term. Therefore, you should take it between 4 and 6 weeks to see benefits, although it is recommended to take glucosamine for at least 2 months. Achieving glucosamine properties in the short term is impossible, unlike what happens with medicinal herbs and pain relievers. It is a supplement that requires some patience and consistency in administration. But the good thing is that even after stopping it, its effects are felt for a long time. Cartilage grows very slowly, and thus everything that affects joint function tends to have a slow recovery process.
As for people who get good results, many seem to benefit, while another group finds no benefits from taking glucosamine sulfate. Unfortunately, there are no parameters that can indicate in which cases it works and in which it doesn’t, so for a patient to observe if it works for them, they must try it and draw their own conclusions and opinions.
Does it work as a treatment for arthritis and osteoarthritis?
It is always best to have a specialist recommend it. This way, they can monitor progress and assess the products and medications that are having an effect on your condition.
Glucosamine for arthritis can counter some of the inflammatory and destructive symptoms of cartilage. This disease causes inflammation and pain due to cartilage wear. Its anti-inflammatory and regenerative properties can be used in both humans and animals, such as dogs and cats. It is also common to combine it with chondroitin, which we describe later.
Some of the most common symptoms of arthritis are cartilage degeneration and joint stiffness. The reduction of cartilage leads to a lack of protection for the bones during movement, which can cause damage. This results in pain, inflammation, and discomfort when performing everyday tasks. Even making them impossible to do. To alleviate the pain and try to improve joint health, an appropriate treatment should be followed, which in many cases can be supported with glucosamine.
Side Effects
It is a very safe molecule, and most people do not experience adverse effects. However, precautions should always be taken, and administration guidelines should be followed. In some cases, the following side effects may occur:
- Stomach pain.
- Feeling nauseous.
- Heartburn.
- Diarrhea.
- Constipation.
These symptoms are generally very mild when they occur and happen in few cases, as indicated by clinical tests and analysis, although they are always possible. Be extra cautious when taking a joint supplement for the first time to avoid allergies or control them if they occur.
Contraindications
As with side effects, glucosamine contraindications are very low and almost nonexistent, although some people should avoid its use:
- If you are pregnant or breastfeeding.
- If you have high cholesterol, consult a doctor. There are no studies showing its interaction, but there are some concerns about it.
- If you are allergic to shellfish or fish. It is typically derived from marine sources, specifically shellfish, so be cautious if you have a food allergy.
- If you are taking anticoagulants.
- If you are undergoing cancer treatments.
This is a brief summary of interactions and potential risk groups, but you can find all the side effects of taking glucosamine to use it safely.
Glucosamine in sachets, capsules, or powder
You can find various brands and products sold in online stores and herb shops, where glucosamine is available in single-dose sachets, powder jars, or capsules of 1500 mg. and other sizes. The main difference is the way it is taken, not its effects, so regardless of the type you buy, you will get its beneficial effects on health.
Glucosamine Sulfate and Glucosamine Hydrochloride
Although different chemical forms can be found, such as glucosamine sulfate, hydrochloride, glucosamine hydrochloride, and its acetylated form, the most common is sulfate.
It is important to choose the right form because, although their properties are similar, they have some differences when they enter the body. Almost all scientific studies and research use glucosamine sulfate, so it is more beneficial to take this form, as it seems to provide the best results in people.
The molecular structure is somewhat different, so it interacts with organic molecules, producing diverse reactions.
The types of glucosamine you can buy are:
- Sulfate
- Hydrochloride
- Acetyl
- Chloride
Are there other joint supplements?
Today, there is a wide variety of products that can aid in the recovery from knee injuries and cartilage tears. Some of these products contain collagen, shark cartilage, glucosamine sulfate, chondroitin, and MSM. Each of these products offers different properties that can help in recovery and slowing the progression of the disease. Collagen, for example, is good for arthritic joints and also improves the skin. Shark cartilage is anti-inflammatory and regenerative. Glucosamine, chondroitin, and MSM are more focused on cartilage recovery and reducing inflammation in connective tissue.
If you have doubts about which one to use, glucosamine sulfate is a very good option and there is no need to add other medicinal molecules, although some people prefer to do so. A good piece of advice is to read the full description, see the properties of each chondroprotector, and compare it with your current situation, symptoms, and discomforts, as well as the benefits you hope to achieve. In general, medicinal products contain chondroprotectors and glucosaminoglycans like hyaluronic acid.
Glucosamine and Chondroitin
This is perhaps the most common combination and the one that gives the best results, according to the opinions of people who take glucosamine with other joint supplements. It is quite common to use it for arthritis and knee injuries such as patellofemoral chondromalacia and cartilage tears, osteoarthritis, etc.
When you take glucosamine and chondroitin, the effects are anti-inflammatory. The tendons and muscle fibers involved in joint movement suffer less and reduce inflammation. This is because chondroitin sulfate also belongs to the group of chondroprotectors. Substances that promote better joint health and cartilage regeneration. If you’re interested in learning more about these two compounds, you can find all the information at glucosamine and chondroitin.
Glucosamine Dosage
The most common amount is to use 1500 mg tablets for the treatment of osteoarthritis and osteoarthritis. This dose is daily and can be divided into three 500 mg doses to be taken with breakfast, lunch, and dinner. However, it is always advisable to have a specialist indicate the amount to suit your ailments or the goals you want to achieve. People who are looking to prevent cartilage wear may benefit from lower doses.