{"id":4872,"date":"2025-03-11T18:58:55","date_gmt":"2025-03-11T17:58:55","guid":{"rendered":"https:\/\/www.mismumi.com\/en\/?p=4872"},"modified":"2025-02-04T15:39:35","modified_gmt":"2025-02-04T14:39:35","slug":"tretinoin-topical-cream","status":"publish","type":"post","link":"https:\/\/www.mismumi.com\/en\/tretinoin-topical-cream\/","title":{"rendered":"Tretinoin topical cream: uses for acne, skin spots, wrinkles, and stretch marks. Don&#8217;t miss the recommendations."},"content":{"rendered":"<p><strong>Tretinoin<\/strong> is an active ingredient used for the treatment of acne and aging skin. Its topical cream form is very common for treating the appearance of pimples, blackheads, or blemishes, as well as for removing spots on the face.<\/p><aside class=\"adsini\"><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><!-- ah_inicio_articulo --><ins class=\"adsbygoogle ah-inicio-articulo\" style=\"display:block\" data-ad-client=\"ca-pub-9582652217436894\"\r\n     data-ad-slot=\"2508209597\" data-ad-format=\"auto\" data-full-width-responsive=\"true\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/aside>\n<p>Its effects, both before and after, are very noticeable, which is why it is currently widely used to rejuvenate the skin and treat many symptoms of skin rashes that may be accompanied by pus.<\/p>\n<div id=\"toc_container\" class=\"toc_white no_bullets\"><p class=\"toc_title\">Contents<\/p><ul class=\"toc_list\"><li><a href=\"#What-is-tretinoin-and-what-is-it-used-for\"><span class=\"toc_number toc_depth_1\">1<\/span> What is tretinoin and what is it used for?<\/a><\/li><li><a href=\"#Uses-of-tretinoin-cream\"><span class=\"toc_number toc_depth_1\">2<\/span> Uses of tretinoin cream<\/a><ul><li><a href=\"#For-acne\"><span class=\"toc_number toc_depth_2\">2.1<\/span> For acne<\/a><\/li><li><a href=\"#For-wrinkles\"><span class=\"toc_number toc_depth_2\">2.2<\/span> For wrinkles<\/a><\/li><li><a href=\"#For-stretch-marks\"><span class=\"toc_number toc_depth_2\">2.3<\/span> For stretch marks<\/a><\/li><li><a href=\"#Uses-for-skin-spots\"><span class=\"toc_number toc_depth_2\">2.4<\/span> Uses for skin spots<\/a><\/li><\/ul><\/li><li><a href=\"#How-to-use-topical-tretinoin\"><span class=\"toc_number toc_depth_1\">3<\/span> How to use topical tretinoin<\/a><\/li><li><a href=\"#Recommended-daily-dose\"><span class=\"toc_number toc_depth_1\">4<\/span> Recommended daily dose<\/a><\/li><li><a href=\"#Usage-Recommendations\"><span class=\"toc_number toc_depth_1\">5<\/span> Usage Recommendations<\/a><\/li><li><a href=\"#Do-tretinoin-capsules-have-the-same-effects\"><span class=\"toc_number toc_depth_1\">6<\/span> Do tretinoin capsules have the same effects?<\/a><\/li><li><a href=\"#Side-Effects\"><span class=\"toc_number toc_depth_1\">7<\/span> Side Effects<\/a><\/li><\/ul><\/div>\n\n<h2><span id=\"What-is-tretinoin-and-what-is-it-used-for\">What is tretinoin and what is it used for?<\/span><\/h2>\n<p>It is an active ingredient, an acid <strong>derived from vitamin A<\/strong>, with effects against severe acne. Tretinoin removes dirt from the pores, reducing the symptoms of acne, although it is not a treatment that cures it permanently.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-98442 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/topical-tretinoin.jpg\" alt=\"What is tretinoin and what is it used for?\" width=\"700\" height=\"300\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/topical-tretinoin.jpg 700w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/topical-tretinoin-336x144.jpg 336w\" sizes=\"(max-width: 700px) 100vw, 700px\" title=\"\"><\/p>\n<p>Known as holo-transretinoic acid (<em>ATRA<\/em>), <strong>tretinoin also has uses for wrinkles, stretch marks, and rosacea<\/strong> in its isotretinoin form. It is also an active substance related to <strong>retinoic acid<\/strong>. All these substances are derivatives of vitamin A, so they share many of its properties and benefits when applied to the skin.<\/p>\n<h2><span id=\"Uses-of-tretinoin-cream\">Uses of tretinoin cream<\/span><\/h2>\n<p>Its most common commercial and medicinal form is <strong>tretinoin cream<\/strong>. It is also available as a gel or liquid to use as a lotion.<\/p><div class=\"clear\"><\/div><center><aside class=\"ads2\"><ins class=\"adsbygoogle\" style=\"display:block; text-align:center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"1797353553\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/aside><\/center><div class=\"clear\"><\/div>\n<p>This vitamin A derivative works by activating the skin cells, encouraging them to repair the skin lesions on the superficial dermal stratum corneum of the epidermis.<\/p>\n<p><strong>The tretinoin cream should be used with caution<\/strong> when recommended by a dermatologist or doctor, as it can cause serious side effects.<\/p>\n<p>When applied to the face, it increases the renewal of the epidermis. Old cells are replaced by new ones that restore and remove marks and scars from the face.<\/p>\n<p><strong>With this commercial form (<em>topical tretinoin cream<\/em>), it can be used in the following cases:<\/strong><\/p>\n<h3><span id=\"For-acne\">For acne<\/span><\/h3>\n<p>Most retinoids and acids <strong>related to retinol<\/strong> are effective at eliminating pimples. They are considered anti-acne treatments, producing very good results depending on their purity and concentration.<\/p><div class=\"clear\"><\/div><center><!-- ah_3_ads --><ins class=\"adsbygoogle\" style=\"display:block\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"7212672277\" data-ad-format=\"auto\" data-full-width-responsive=\"true\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/aside><\/center><div class=\"clear\"><\/div>\n<p><strong>Tretinoin for mild, severe, and hormonal acne in adults and teenagers is effective and works<\/strong>, and thousands of dermatologists know this, recommending its use when necessary.<\/p>\n<p>The catch is that it is quite strong and you need to be careful with its use. Both tretinoin 0.025 and 0.05 are widely used to treat acne, just like <a href=\"https:\/\/www.mismumi.com\/adapaleno\/\"><strong>topical adapalene<\/strong><\/a>, which prevents the eruption of sebum and the formation of new pimples. You can use this in cream, ointment, or gel form.<\/p>\n<h3><span id=\"For-wrinkles\">For wrinkles<\/span><\/h3>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-98443 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/wrinkles-on-face.jpg\" alt=\"How to remove wrinkles on the face with tretinoin\" width=\"336\" height=\"280\" title=\"\"><br \/>\nIt produces a mild chemical exfoliation, causing the stratum corneum of the skin to renew. Tretinoin for wrinkles is a retinoid formulation known as <a href=\"https:\/\/www.mismumi.com\/en\/retinoic-acid\/\"><strong>retinoic acid<\/strong><\/a>.<\/p>\n<p>When you apply it to the skin, it absorbs fairly easily. Since retinoic acid is the pure form, that is, the <em>pure acid<\/em>, it does not need a chemical transformation in the body to penetrate and act on the tissues, which is why it is much more effective even when used in cream form.<\/p>\n<p><strong>Tretinoin for wrinkles is indicated in some cases<\/strong>, although its major use is as a treatment for acne. It is also used for psoriasis.<\/p>\n<p>This formula has more direct effects on the formation of pimples, and for wrinkles, it might be better to use one of the vitamin A derivatives like <strong><a href=\"https:\/\/www.mismumi.com\/retinol-que-es-propiedades\/\">retinol<\/a><\/strong>, which can be pure or serve as the active ingredient in different anti-aging creams, usually in small concentrations. For wrinkles and expression lines, it is often more convenient to use other types of depigmenting agents or even a <a href=\"https:\/\/www.mismumi.com\/en\/chemical-peel\/\"><strong>chemical peel<\/strong><\/a>, always considering the specific case.<\/p>\n<h3><span id=\"For-stretch-marks\">For stretch marks<\/span><\/h3>\n<p>It reduces skin marks and uneven coloring, hyperpigmentation. In its topical form, gel or cream, <strong>Retin-A tretinoin is used for stretch marks<\/strong>.<\/p>\n<p><strong>After 2 or 3 months, the results are visible<\/strong>. Before that, they are very mild, with redness of the skin and tingling possibly appearing, especially during the first days of application.<\/p>\n<p>From <strong>8 weeks of use<\/strong>, the reduction of the stretch mark becomes noticeable when comparing the before and after.<\/p>\n<p>When the stretch marks to be treated are large and numerous, it is often advisable to undergo an alternative treatment. One that works much faster and more effectively.<\/p>\n<p>For example, to <a href=\"https:\/\/www.mismumi.com\/laser-fraxel-dual-estrias-cicatrices\/\"><strong>remove white stretch marks, Fraxel laser<\/strong><\/a> provides very good results. It works much better, and after some time, when the skin has recovered, the tretinoin cream can be applied to reinforce the results and finish eliminating the stretch marks.<\/p>\n<h3><span id=\"Uses-for-skin-spots\">Uses for skin spots<\/span><\/h3>\n<p>It is the same case as with a stretch mark or small facial scars. Using <strong>tretinoin for spots reduces<\/strong> hyperpigmentation or white skin that appears due to a lack of melanin, known as hypopigmentation.<\/p>\n<p>With the lack of melanin, the causes need to be observed, as in the case where melanocytes are scarce or unable to produce pigments, tretinoin treatment will not work as expected.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-98444 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/skin-spots.jpg\" alt=\"Skin spots before and after tretinoin treatment\" width=\"336\" height=\"280\" title=\"\"><\/p>\n<p>It should be noted that if the disorder causing excess melanin in the skin (<em>hyperpigmentation<\/em>) continues after using tretinoin or isotretinoin, spots may reappear on the face or body area where the treatment with the retinoid was performed.<\/p>\n<p><strong>For good results, the causes that lead to the gathering of skin pigments must be addressed<\/strong>. Otherwise, these will form and group again.<\/p>\n<p>Vitamin A derivatives help regenerate the skin, which includes the disappearance of spots and expression signs, but not the causes that generate them.<\/p>\n<h2><span id=\"How-to-use-topical-tretinoin\">How to use topical tretinoin<\/span><\/h2>\n<p><img loading=\"lazy\" class=\"aligncenter size-full wp-image-98447\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/tretinoin-topical-cream-0-05.jpg\" alt=\"Tretinoin topical cream 0,05\" width=\"720\" height=\"300\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/tretinoin-topical-cream-0-05.jpg 720w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/tretinoin-topical-cream-0-05-336x140.jpg 336w\" sizes=\"(max-width: 720px) 100vw, 720px\" title=\"\"><\/p>\n<ol>\n<li>Clean the skin with water and mild or neutral soap.<\/li>\n<li>Apply a small amount of product to the affected skin, gently massaging.<\/li>\n<li>Let it act overnight.<\/li>\n<\/ol>\n<p>After several hours, when you wake up, you can wash your face or the treated skin area with plenty of water.<\/p>\n<h2><span id=\"Recommended-daily-dose\">Recommended daily dose<\/span><\/h2>\n<ul>\n<li>Apply the cream or ointment once a night before sleeping.<\/li>\n<\/ul>\n<p>Exceptionally, the dermatologist may recommend doubling the <strong>tretinoin dose<\/strong> to 2 applications a day for <strong>acne<\/strong>. One in the morning and another at night before going to bed. This recommendation is generally for severe acne cases. Low doses are for when there are few pimples and the acne is mild.<\/p>\n<p><strong>For photoaging<\/strong> (<em>spots, stretch marks, and everything related to aging skin<\/em>), only one daily use is required. Always at night so it can work for several hours.<\/p>\n<p>Depending on the symptoms of the person, the dose may change. Always consult with your doctor to know the exact amount you should use and do not modify it without informing them. It is crucial to follow all the treatment instructions for it to work properly.<\/p>\n<h2><span id=\"Usage-Recommendations\">Usage Recommendations<\/span><\/h2>\n<p><img loading=\"lazy\" class=\"aligncenter size-full wp-image-98445\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/tretinoin-uses.jpg\" alt=\"Tretinoin dosage, indications, and frequency of use\" width=\"336\" height=\"280\" title=\"\"><\/p>\n<p><strong>Always use sunscreen with full coverage during the day to prevent skin spots from forming.<\/strong><\/p>\n<p>By removing the outer layer of the epidermis (<em>stratum corneum<\/em>), you will be much more sensitive to the effects of sunlight. Ultraviolet radiation will stimulate more melanin to form in the regenerated areas. If you don&#8217;t use sunscreen with a high protection factor (SPF +50), it is very likely that spots will appear, and you may even develop sunburn.<\/p>\n<p><strong>It is very important to protect your skin during tretinoin cream treatment and the following weeks.<\/strong><\/p>\n<h2><span id=\"Do-tretinoin-capsules-have-the-same-effects\">Do tretinoin capsules have the same effects?<\/span><\/h2>\n<p>With this form <strong>the effects of tretinoin are much stronger<\/strong> and are indicated for cancer treatment. Oral administration should always be prescribed by a cancer specialist. Only topical use is recommended for mild conditions, acne, imperfections, wrinkles, etc.<\/p>\n<h2><span id=\"Side-Effects\">Side Effects<\/span><\/h2>\n<ul>\n<li>Skin irritation.<\/li>\n<li>Itching.<\/li>\n<li>Pruritus or difficult-to-control itching.<\/li>\n<li>Stinging.<\/li>\n<li>Redness.<\/li>\n<li>Peeling.<\/li>\n<li>Liver damage when administered orally (<em>capsules<\/em>).<\/li>\n<\/ul>\n<p>It is very common for <strong>the first applications<\/strong> to cause side effects from tretinoin. Being an acid, it damages the skin so it can regenerate. This causes mild discomfort and adverse reactions that can generally be tolerated without additional medication. Applying it at night makes the possible side effects and adverse reactions much more bearable.<\/p>\n<p>If you notice an excessive reaction or if pain, rash, and other types of rejection appear, you should see a doctor to stop the treatment or adjust the daily dose. In many cases, spacing out the applications will be enough.<\/p>\n<\/p><aside class=\"ads\"><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><!-- ah_fin_articulo --><ins class=\"adsbygoogle ah-fin-articulo\" style=\"display:inline-block\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"4055871191\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/aside><aside class=\"ads-relacionado\"><center><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><!-- mismumi_relacionado --><ins class=\"adsbygoogle\" style=\"display:block\" data-ad-format=\"autorelaxed\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"2966766890\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/center><\/aside><div class=\"clear\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Tretinoin is an active ingredient used for the treatment of acne and aging skin. Its topical cream form is very common for treating the appearance of pimples, blackheads, or blemishes, as well as for&#46;&#46;&#46;<\/p>\n","protected":false},"author":7,"featured_media":98442,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[57,56],"tags":[],"_links":{"self":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/posts\/4872"}],"collection":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/comments?post=4872"}],"version-history":[{"count":0,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/posts\/4872\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/media\/98442"}],"wp:attachment":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/media?parent=4872"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/categories?post=4872"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/tags?post=4872"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}