{"id":1384,"date":"2024-09-04T07:50:21","date_gmt":"2024-09-04T05:50:21","guid":{"rendered":"https:\/\/www.mismumi.com\/en\/?p=1384"},"modified":"2024-09-04T10:49:28","modified_gmt":"2024-09-04T08:49:28","slug":"retinoic-acid","status":"publish","type":"post","link":"https:\/\/www.mismumi.com\/en\/retinoic-acid\/","title":{"rendered":"Retinoic Acid: Uses, Properties, and Effects of Creams"},"content":{"rendered":"<p>The <strong>retinoic acid<\/strong> (RA) is a derivative or metabolite of vitamin A. Well known as retinol and used in numerous anti-spot and anti-wrinkle creams or as a lotion, it also has a role in the human body, specifically in embryo development.<\/p><aside class=\"adsini\"><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><!-- ah_inicio_articulo --><ins class=\"adsbygoogle ah-inicio-articulo\" style=\"display:block\" data-ad-client=\"ca-pub-9582652217436894\"\r\n     data-ad-slot=\"2508209597\" data-ad-format=\"auto\" data-full-width-responsive=\"true\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/aside>\n<p>In cosmetics, it is used as a depigmenting agent to eliminate skin hyperpigmentation and as a treatment to remove facial spots, and it is also used to treat acne. It acts as a bleaching agent by removing the outer layer of the skin, being very effective in fighting skin imperfections and as a peeling product.<br \/>\n<div id=\"toc_container\" class=\"toc_white no_bullets\"><p class=\"toc_title\">Contents<\/p><ul class=\"toc_list\"><li><a href=\"#What-is-Retinoic-Acid-Used-For\"><span class=\"toc_number toc_depth_1\">1<\/span> What is Retinoic Acid Used For<\/a><ul><li><a href=\"#Retinoic-Acid-in-Creams\"><span class=\"toc_number toc_depth_2\">1.1<\/span> Retinoic Acid in Creams<\/a><ul><li><a href=\"#What-Retinoic-Acid-in-Creams-is-Used-For\"><span class=\"toc_number toc_depth_3\">1.1.1<\/span> What Retinoic Acid in Creams is Used For<\/a><\/li><\/ul><\/li><li><a href=\"#Role-of-Retinoic-Acid-in-Development\"><span class=\"toc_number toc_depth_2\">1.2<\/span> Role of Retinoic Acid in Development<\/a><\/li><\/ul><\/li><li><a href=\"#Uses-of-Retinoic-Acid\"><span class=\"toc_number toc_depth_1\">2<\/span> Uses of Retinoic Acid<\/a><ul><li><a href=\"#Acne\"><span class=\"toc_number toc_depth_2\">2.1<\/span> Acne<\/a><\/li><li><a href=\"#Uses-as-a-Depigmenting-Agent\"><span class=\"toc_number toc_depth_2\">2.2<\/span> Uses as a Depigmenting Agent<\/a><\/li><li><a href=\"#Skin-Spots\"><span class=\"toc_number toc_depth_2\">2.3<\/span> Skin Spots<\/a><\/li><li><a href=\"#Peeling-for-Spots-and-Scars\"><span class=\"toc_number toc_depth_2\">2.4<\/span> Peeling for Spots and Scars<\/a><\/li><li><a href=\"#Psoriasis\"><span class=\"toc_number toc_depth_2\">2.5<\/span> Psoriasis<\/a><\/li><li><a href=\"#Use-with-Tretinoin\"><span class=\"toc_number toc_depth_2\">2.6<\/span> Use with Tretinoin<\/a><\/li><li><a href=\"#With-Hydroquinone\"><span class=\"toc_number toc_depth_2\">2.7<\/span> With Hydroquinone<\/a><\/li><li><a href=\"#Alpha-Bisabolol\"><span class=\"toc_number toc_depth_2\">2.8<\/span> Alpha Bisabolol<\/a><\/li><li><a href=\"#Dexamethasone\"><span class=\"toc_number toc_depth_2\">2.9<\/span> Dexamethasone<\/a><\/li><li><a href=\"#Fluocinolone\"><span class=\"toc_number toc_depth_2\">2.10<\/span> Fluocinolone<\/a><\/li><li><a href=\"#Retinoic-Acid-and-Glycolic-Acid-Together\"><span class=\"toc_number toc_depth_2\">2.11<\/span> Retinoic Acid and Glycolic Acid Together<\/a><\/li><\/ul><\/li><li><a href=\"#Synthesis-of-Retinoic-Acid-How-Do-We-Obtain-It\"><span class=\"toc_number toc_depth_1\">3<\/span> Synthesis of Retinoic Acid: How Do We Obtain It?<\/a><\/li><li><a href=\"#Is-It-Effective\"><span class=\"toc_number toc_depth_1\">4<\/span> Is It Effective?<\/a><\/li><li><a href=\"#Side-Effects-of-Retinoic-Acid\"><span class=\"toc_number toc_depth_1\">5<\/span> Side Effects of Retinoic Acid<\/a><\/li><li><a href=\"#Should-You-Stop-Using-It-if-It-Itches-or-Burns\"><span class=\"toc_number toc_depth_1\">6<\/span> Should You Stop Using It if It Itches or Burns?<\/a><\/li><li><a href=\"#Contraindications\"><span class=\"toc_number toc_depth_1\">7<\/span> Contraindications<\/a><\/li><li><a href=\"#Is-retinoic-acid-the-same-as-retinol\"><span class=\"toc_number toc_depth_1\">8<\/span> Is retinoic acid the same as retinol?<\/a><\/li><li><a href=\"#Best-Retinoic-Acid-Creams\"><span class=\"toc_number toc_depth_1\">9<\/span> Best Retinoic Acid Creams<\/a><\/li><li><a href=\"#Commercial-Names-and-Other-Retinoids\"><span class=\"toc_number toc_depth_1\">10<\/span> Commercial Names and Other Retinoids<\/a><\/li><li><a href=\"#When-Will-the-Benefits-or-Results-Be-Perceived\"><span class=\"toc_number toc_depth_1\">11<\/span> When Will the Benefits or Results Be Perceived?<\/a><\/li><li><a href=\"#How-to-Use-Retinoic-Acid-Creams\"><span class=\"toc_number toc_depth_1\">12<\/span> How to Use Retinoic Acid Creams<\/a><\/li><li><a href=\"#Precautions-and-Usage-Recommendations\"><span class=\"toc_number toc_depth_1\">13<\/span> Precautions and Usage Recommendations<\/a><\/li><li><a href=\"#Probable-Reactions\"><span class=\"toc_number toc_depth_1\">14<\/span> Probable Reactions<\/a><\/li><li><a href=\"#Price-of-Retinoic-Acid\"><span class=\"toc_number toc_depth_1\">15<\/span> Price of Retinoic Acid<\/a><\/li><\/ul><\/div>\n<\/p>\n<h2><span id=\"What-is-Retinoic-Acid-Used-For\">What is Retinoic Acid Used For<\/span><\/h2>\n<p>It is one of the most commonly used <a href=\"https:\/\/www.mismumi.com\/en\/other-categories\/acids\/\" rel=\"nofollow\">cosmetic acids<\/a> as a <strong>facial depigmenting agent<\/strong>. It works by removing the outer layer of the skin and destroying old cells and clusters of melanin that cause brown and red spots. Retinoic acid activates the production of natural collagen and is closely related to tretinoin.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97239 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid.jpg\" alt=\"Retinoic Acid\" width=\"720\" height=\"495\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid.jpg 720w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-336x231.jpg 336w\" sizes=\"(max-width: 720px) 100vw, 720px\" title=\"\"><\/p>\n<p>We can distinguish two functions or uses of retinoic acid:<\/p>\n<ul>\n<li>Uses in cosmetics.<\/li>\n<li>Role in human body development.<\/li>\n<\/ul>\n<h3><span id=\"Retinoic-Acid-in-Creams\">Retinoic Acid in Creams<\/span><\/h3>\n<p>As an active ingredient, <strong>creams with retinoic acid<\/strong> have anti-aging effects. Like vitamin A, it acts on the skin, causing peeling and thereby removing pimples and imperfections as well as small marks caused by blackheads, whiteheads, and other skin disorders.<\/p><div class=\"clear\"><\/div><center><aside class=\"ads2\"><ins class=\"adsbygoogle\" style=\"display:block; text-align:center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"1797353553\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/aside><\/center><div class=\"clear\"><\/div>\n<p><strong>Retinoic acid<\/strong>, often referred to as tretinoin \u2013<em>though they are not exactly the same\u2013<\/em> was discovered by <a href=\"https:\/\/en.wikipedia.org\/wiki\/Albert_Kligman\" target=\"_blank\" rel=\"noopener\">Albert Kligman<\/a> in 1973. It was used to treat acne.<\/p>\n<p>Since then, due to its effectiveness, its uses have expanded, and it can now be found in creams with retinoic acid for removing pimples and blackheads, as well as for treating facial imperfections.<\/p>\n<h4><span id=\"What-Retinoic-Acid-in-Creams-is-Used-For\">What Retinoic Acid in Creams is Used For<\/span><\/h4>\n<ul>\n<li>To remove skin spots.<\/li>\n<li>Reduce hyperpigmentation.<\/li>\n<li>Improve skin tone.<\/li>\n<li>Eliminate wrinkles.<\/li>\n<li>Stimulate natural collagen synthesis.<\/li>\n<li>Block free radicals (<em>antioxidant function<\/em>).<\/li>\n<\/ul>\n<p>Its <a href=\"https:\/\/www.mismumi.com\/en\/nutrition\/antioxidants\/\" rel=\"nofollow\">antioxidant properties<\/a> work by blocking free radicals that damage the skin daily. It halts the oxidation process and prevents the appearance of such harmful molecules, which cause premature aging due to solar radiation and age.<\/p><div class=\"clear\"><\/div><center><!-- ah_3_ads --><ins class=\"adsbygoogle\" style=\"display:block\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"7212672277\" data-ad-format=\"auto\" data-full-width-responsive=\"true\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/aside><\/center><div class=\"clear\"><\/div>\n<p>As a <strong>collagen synthesis activator<\/strong>, by removing the outer layers of the skin, it stimulates the body to produce more collagen, an essential protein for smoother and softer skin, with more elasticity and less sagging or facial laxity (senile elastosis), the atrophy of the skin caused by aging where elastin and collagen fibers lose their vigor.<\/p>\n<p>Against skin laxity or sagging, retinoic acid improves the quality of elastin by increasing the activity of fibroblasts, cells responsible for synthesizing collagen and hyaluronic acid.<\/p>\n<p>Another property of retinoic acid is its function as a depigmenting agent. If you have spots on your face, small scars from pimples, and other facial irregularities, applying it will help eliminate them.<\/p>\n<h3><span id=\"Role-of-Retinoic-Acid-in-Development\">Role of Retinoic Acid in Development<\/span><\/h3>\n<p>During embryo development, vitamin A and its metabolite (<em>retinoic acid<\/em>) are necessary. During the growth of vertebrate animals, <em>including humans<\/em>, retinoic acid acts as an intercellular signaling molecule, guiding embryonic development and preventing fetal malformations (<a href=\"https:\/\/es.wikipedia.org\/wiki\/Teratog%C3%A9nesis\" target=\"_blank\" rel=\"noopener\">teratogenic effect<\/a>).<\/p>\n<h2><span id=\"Uses-of-Retinoic-Acid\">Uses of Retinoic Acid<\/span><\/h2>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97240 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-structure.jpg\" alt=\"Retinoic Acid structure\" width=\"300\" height=\"87\" title=\"\"><\/p>\n<ul>\n<li>Treat acne.<\/li>\n<li>Depigment the skin.<\/li>\n<li>Remove facial spots.<\/li>\n<li>Improve skin tone.<\/li>\n<li>Treatment for psoriasis.<\/li>\n<li>Treatment for myeloid leukemia.<\/li>\n<li>With tretinoin.<\/li>\n<li>With hydroquinone.<\/li>\n<li>Alpha bisabolol.<\/li>\n<li>Dexamethasone.<\/li>\n<li>Fluocinolone.<\/li>\n<\/ul>\n<p>In both cases or uses, retinoic acid promotes cell renewal, <strong>delaying aging and making the skin appear younger<\/strong>. This effect is due to increased collagen production and thickening of the epidermis.<\/p>\n<p>Applying topical retinoic acid through a cream evens out skin tone. After a few weeks of use, results become quite evident.<\/p>\n<p>As mentioned, it is also called tretinoin, a molecule found in many anti-wrinkle creams due to its high effectiveness on the skin. It is one of the best substances with anti-aging effects.<\/p>\n<h3><span id=\"Acne\">Acne<\/span><\/h3>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97241 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-acne.jpg\" alt=\"Retinoic acid for acne: before and after\" width=\"720\" height=\"440\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-acne.jpg 720w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-acne-336x205.jpg 336w\" sizes=\"(max-width: 720px) 100vw, 720px\" title=\"\"><\/p>\n<p>For this purpose, it can be used in concentrations of 0.05% and 0.025%. <strong>Retinoic acid for acne<\/strong> works on comedones, pustules, and papules. It reduces pimples, decreases inflammation, and excess oil.<\/p>\n<p>Dermatologists recommend its use to many people but always under their guidance. It is indicated for the treatment of acne vulgaris of grades I, II, and III.<\/p>\n<p>It should be applied daily by spreading a thin layer of retinoid cream over the pimples or the entire face if necessary, with care around the eyes and mucous membranes.<\/p>\n<h3><span id=\"Uses-as-a-Depigmenting-Agent\">Uses as a Depigmenting Agent<\/span><\/h3>\n<p>It is effective as a skin depigmenting agent. Its action is similar to that for acne; <strong>apply a small amount of retinoic acid every night<\/strong> to facial spots. This will start skin renewal from the second week, making it noticeably smoother and with a more youthful color.<\/p>\n<p>Since collagen production is slow, results are seen in the medium term, and the depigmenting treatment should be continued for complete effects.<\/p>\n<h3><span id=\"Skin-Spots\">Skin Spots<\/span><\/h3>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97242 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-for-skin-spots.jpg\" alt=\"Retinoic Acid for Skin Spots\" width=\"720\" height=\"440\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-for-skin-spots.jpg 720w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-for-skin-spots-336x205.jpg 336w\" sizes=\"(max-width: 720px) 100vw, 720px\" title=\"\"><\/p>\n<p>One advantage is that since it works very well as a depigmenting agent, <strong>retinoic acid for skin spots is highly effective<\/strong>. It removes the outer layers of the epidermis, reducing melanin and pigment clusters that cause dark or red coloration.<\/p>\n<p>Spots from acne and those caused by aging can be treated with this acid, both in cream form and through peeling applications. It removes facial spots and evens out the tone of the cheeks, forehead, and other areas where applied.<\/p>\n<h3><span id=\"Peeling-for-Spots-and-Scars\">Peeling for Spots and Scars<\/span><\/h3>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97243 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/peeling-retinoic-acid.jpg\" alt=\"Application of Retinoic Acid Peel\" width=\"720\" height=\"300\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/peeling-retinoic-acid.jpg 720w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/peeling-retinoic-acid-336x140.jpg 336w\" sizes=\"(max-width: 720px) 100vw, 720px\" title=\"\"><\/p>\n<p>It can be used as a <strong><a href=\"https:\/\/www.mismumi.com\/en\/chemical-peel\/\">chemical peeling<\/a><\/strong> product. To do this, a layer of retinoic acid should be spread over the entire facial skin, taking great care around mucous membranes and areas near the eyes and lips.<\/p>\n<p><strong>Using retinoic acid for peeling<\/strong> and as a cream to remove facial spots should be done by a dermatologist or, alternatively, using one of the commercially prepared cosmetics for this purpose. Commercial retinoid creams generally contain a low concentration of the active substance, ideal for home use when a full dermatological treatment is not needed.<\/p>\n<h3><span id=\"Psoriasis\">Psoriasis<\/span><\/h3>\n<p>Retinoids like acitretin are used to treat psoriasis. It should always be used under medical supervision due to its potential teratogenic effects, which could cause fetal malformations if you are pregnant.<\/p>\n<h3><span id=\"Use-with-Tretinoin\">Use with Tretinoin<\/span><\/h3>\n<p>As previously indicated, retinoic acid is closely related to <a href=\"https:\/\/www.mismumi.com\/en\/tretinoin-topical-cream\/\"><strong>tretinoin<\/strong><\/a> and also to isotretinoin (<em>13-cis-retinoic acid<\/em>). Both tretinoin and isotretinoin have somewhat different molecular structures. They are isomers of retinoic acid.<\/p>\n<h3><span id=\"With-Hydroquinone\">With Hydroquinone<\/span><\/h3>\n<p>In many cases, it is possible to alternate the use of different depigmenting agents like retinoic acid and <strong><a href=\"https:\/\/www.mismumi.com\/en\/hydroquinone-cream-gel-ointment\/\">hydroquinone<\/a><\/strong> (<em>1.4-dihydroxybenzene<\/em>), a chemical compound used to treat skin hyperpigmentation and reduce dark spots caused by excess melanin and melanocytes in certain areas of the body.<\/p>\n<p>Hydroquinone is a <strong>skin lightening agent<\/strong> that should be used in cream form with a concentration of less than 2%, and like retinoids, it should be used under the supervision of a dermatologist.<\/p>\n<p>Unless the cream you purchase already contains a mixture of hydroquinone and retinoic acid, these two products should never be used together. Their application enhances the effects as they act similarly.<\/p>\n<h3><span id=\"Alpha-Bisabolol\">Alpha Bisabolol<\/span><\/h3>\n<p>In this case, it is a calming active ingredient with anti-inflammatory properties. The use of retinoic acid, hydroquinone, and alpha bisabolol improves the sensation of stinging, reducing some of the side effects associated with retinoids.<\/p>\n<p>Many creams include these components, with <a href=\"https:\/\/www.mismumi.com\/en\/alpha-bisabolol\/\"><strong>alpha bisabolol<\/strong><\/a> being key to enhancing the effectiveness of other active substances while reducing irritation caused by depigmenting agents.<\/p>\n<h3><span id=\"Dexamethasone\">Dexamethasone<\/span><\/h3>\n<p>It works <em>similarly<\/em> to bisabolol. A cream containing retinoic acid, hydroquinone, and dexamethasone has the ability to lighten the skin while reducing redness and the burning sensation characteristic of vitamin A derivatives.<\/p>\n<p>Like the other compounds, it should always be used topically when included in a commercial preparation.<\/p>\n<h3><span id=\"Fluocinolone\">Fluocinolone<\/span><\/h3>\n<p>It is a Grade III corticosteroid with anti-inflammatory properties. <strong>Fluocinolone<\/strong> is widely used in dermatology due to its ability to reduce itching, skin redness, and other discomforts associated with retinoids. A cream with retinoic acid and fluocinolone has the same base as those with alpha bisabolol and dexamethasone, that is, to mitigate some of the side effects of topical retinoids.<\/p>\n<h3><span id=\"Retinoic-Acid-and-Glycolic-Acid-Together\">Retinoic Acid and Glycolic Acid Together<\/span><\/h3>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97244 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/glycolic-acid-structure.jpg\" alt=\"Chemical Structure of Glycolic Acid\" width=\"336\" height=\"280\" title=\"\"><\/p>\n<p>Glycolic acid enhances the action of retinoic acid. Combining various cosmetic acids amplifies the properties of both, as well as collagen formation. Using retinoic acid and glycolic acid together increases the removal of the stratum corneum, promoting skin tissue regeneration.<\/p>\n<p>The so-called AHA acids, including <a href=\"https:\/\/www.mismumi.com\/en\/glycolic-acid\/\"><strong>glycolic acid<\/strong><\/a>, are widely used as cosmetic products for peeling and inducing skin exfoliation.<\/p>\n<p>The combination of these two chemical compounds enhances effects on neocollagenesis, which is beneficial for skin rejuvenation.<\/p>\n<h2><span id=\"Synthesis-of-Retinoic-Acid-How-Do-We-Obtain-It\">Synthesis of Retinoic Acid: How Do We Obtain It?<\/span><\/h2>\n<p>Although the body can produce it, its origin can be found in plants. Animals and humans ingest it in the form of <strong>beta-carotene<\/strong>.<\/p>\n<p>From the ingestion of food, the body begins a series of chemical reactions that result in the final formula, which <strong>converts the precursors into natural retinoic acid<\/strong>.<\/p>\n<p>Vitamin A and carotenoids need an oxidation process within the human body. But what\u2019s interesting is that once it reaches its final form, <strong>retinoic acid has many benefits and properties for skin tissues<\/strong> and the entire human dermis. Among these benefits, it functions as one of the <strong>best depigmenting agents<\/strong>, meaning it helps eliminate skin spots, reduce excessive pigmentation, <em>known as hyperpigmentation<\/em>, and also, retinoic acid helps even out the skin tone.<\/p>\n<h2><span id=\"Is-It-Effective\">Is It Effective?<\/span><\/h2>\n<p>Since its discovery in 1973, countless studies have demonstrated that retinoic acid works very well. This is why it is still used today. At small doses of 0.05 and 0.025, it has few side effects and can be easily managed when applied topically.<\/p>\n<p>The effectiveness of retinoic acid is based on its ability to halt the degenerative processes of the skin caused by aging and acne. It removes age-related spots and melanin clusters that can be observed on the hands, face, neck, and d\u00e9colletage.<\/p>\n<p>It is also widely used <strong>against acne<\/strong>. Due to its <strong>peeling effect<\/strong>, retinoic acid can eliminate small bumps and imperfections. It can be beneficial if you have many pimples and blackheads. However, in these cases, it is always advisable to get a recommendation from a dermatologist as there may be some incompatibilities.<\/p>\n<h2><span id=\"Side-Effects-of-Retinoic-Acid\">Side Effects of Retinoic Acid<\/span><\/h2>\n<ul>\n<li>Skin peeling.<\/li>\n<li>Redness.<\/li>\n<li>Itching.<\/li>\n<li>Burning.<\/li>\n<li>Loss of appetite.<\/li>\n<li>Irritability.<\/li>\n<li>Kidney dysfunction.<\/li>\n<li>Bone and joint pain.<\/li>\n<li>Congenital malformations.<\/li>\n<\/ul>\n<p>All retinoids should be used with caution as they are likely to cause unwanted reactions. They should be used for a short period and always at low doses. The <strong>side effects of retinoic acid<\/strong> mostly include itching, burning, and irritation of the skin. The initial applications can be somewhat uncomfortable, with a burning sensation.<\/p>\n<p>Misuse of retinoic acid can be dangerous, potentially leading to skin problems and <em>burns<\/em>.<\/p>\n<p>Another side effect of retinoids is hypersensitivity. This appears more prominently at the beginning of treatment, whether used in the form of a cream or as part of a depigmenting serum. Human skin loses sensitivity after contact with this acid. The more you use a retinoid cream, the less effect it has.<\/p>\n<h2><span id=\"Should-You-Stop-Using-It-if-It-Itches-or-Burns\">Should You Stop Using It if It Itches or Burns?<\/span><\/h2>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97245 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/layers-of-the-human-skin.jpg\" alt=\"Layers of the human skin\" width=\"336\" height=\"223\" title=\"\"><\/p>\n<p>Retinoic acid is a potent acid with strong effects on the skin. As mentioned, initial applications for treating acne with a cream containing it may cause itching and burning. However, this does not mean you should stop using it; on the contrary, it indicates that it is working.<\/p>\n<p>As long as you use the correct dosage, it will not cause harm, and after a few days, the unpleasant sensations will disappear, giving way to the beneficial effects against pimples and hyperpigmentation.<\/p>\n<p>In some cases, the dose of retinoic acid might be too strong, so it\u2019s always best to start with a lower concentration cream and, if it\u2019s not effective, acquire one with a higher concentration.<\/p>\n<p>Once you begin using it, your skin will gradually adapt, fulfilling its purpose and improving the quality of the epidermal tissues.<\/p>\n<p>Nevertheless, the concentration in over-the-counter retinol creams available in most stores is usually sufficient to enhance skin health. If you have never used it before, it is best to start with the lowest concentration, that is, 0.025.<\/p>\n<h2><span id=\"Contraindications\">Contraindications<\/span><\/h2>\n<ul>\n<li>Eczema.<\/li>\n<li>Open wounds.<\/li>\n<li>Pregnancy.<\/li>\n<li>Skin infection.<\/li>\n<li>Allergy.<\/li>\n<\/ul>\n<p>If you have wounds, eczema, or any skin condition, you should avoid using it. It is likely to increase irritation and worsen some of your existing symptoms.<\/p>\n<p>Be careful with mucous membranes and the eye area. Never touch them.<\/p>\n<p>To eliminate the side effects of retinoic acid, simply stop the treatment. These effects will disappear on their own after a few hours or days depending on the amount applied.<\/p>\n<h2><span id=\"Is-retinoic-acid-the-same-as-retinol\">Is retinoic acid the same as retinol?<\/span><\/h2>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97246 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinol-creams-serum.jpg\" alt=\"Creams with Retinol and Fluid Serums for Facial Use\" width=\"700\" height=\"300\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinol-creams-serum.jpg 700w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinol-creams-serum-336x144.jpg 336w\" sizes=\"(max-width: 700px) 100vw, 700px\" title=\"\"><\/p>\n<p>At first glance, they may seem the same, but in practice, they are not. Here\u2019s why there are differences between topical vitamin A derivatives.<\/p>\n<p><strong>Retinol<\/strong> is commonly found in anti-wrinkle creams and exfoliants. It is somewhat milder than retinoic acid, so its effects on human skin are softer. This means that side effects are also less frequent and, if they occur, are milder. Overall, retinol has greater tolerance when applied topically.<\/p>\n<p><strong>Being milder, retinol has both advantages and disadvantages<\/strong>. Some people find it easier to use as they don\u2019t experience itching, but others may find it less effective. Tolerance to retinoids varies from person to person, so it is necessary to test it on first application.<\/p>\n<h2><span id=\"Best-Retinoic-Acid-Creams\">Best Retinoic Acid Creams<\/span><\/h2>\n<p>Now let\u2019s discuss the best retinoic acid creams that deliver good results and act against facial spots and correct aging.<\/p>\n<p>Keep in mind that this list may vary depending on the type of skin issue you wish to address. It is created for those looking for a facial cream to remove sun spots and typical skin imperfections caused by aging or excessive sun exposure.<\/p>\n<p>Here is the <strong>list of the best retinol creams<\/strong>:<\/p>\n<ul>\n<li>Avene Ystheal Eye Contour.<\/li>\n<li>Sesderma Sebovalis Facial Cream.<\/li>\n<li>NeoStrata SaliZinc.<\/li>\n<li>Natura Bisse Diamond Life Infusion Retinol Eye Serum.<\/li>\n<li>Chantecaille Retinol Intense.<\/li>\n<li>Skinceuticals Phloretin Retinol.<\/li>\n<\/ul>\n<p>Most of the time, you can buy creams with retinol and vitamin E, along with other antioxidants that are very beneficial for the skin.<\/p>\n<p>Including antioxidants like vitamin E in creams helps stabilize the formula and prevent the degradation of the retinoids in the product. Cosmetics are very volatile and can oxidize with sunlight and air, degrading and losing effectiveness. Therefore, it is very common for retinol and other retinoids to be combined with vitamin E in their commercial presentation.<\/p>\n<h2><span id=\"Commercial-Names-and-Other-Retinoids\">Commercial Names and Other Retinoids<\/span><\/h2>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97247 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-creams.jpg\" alt=\"Brand names of the best creams with retinoic acid\" width=\"700\" height=\"300\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-creams.jpg 700w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/retinoic-acid-creams-336x144.jpg 336w\" sizes=\"(max-width: 700px) 100vw, 700px\" title=\"\"><\/p>\n<p>If you check the label of creams with retinoic acid, you will see that some identify it as retinol, others as retinoids, retinyl, retinyl linoleate, retinol linoleate, retinaldehyde, retinoate, or retinyl propionate.<\/p>\n<p>There is a wide variety of retinoid names, so depending on the patent of the pharmaceutical lab, it may appear as retinoic acid or one of the names mentioned, depending on branding and marketing approaches.<\/p>\n<p>But what is important is that <strong>even if they are not chemically identical, their properties and benefits will be<\/strong>. So make sure the product includes one of the names mentioned.<\/p>\n<p>If you want to see the <strong><a href=\"https:\/\/www.mismumi.com\/en\/best-retinol-creams\/\">best retinol creams<\/a><\/strong>, we have created a list explaining their properties and benefits for specific areas of the face. As mentioned, retinol is a good way to start using skin lighteners, so keep it in mind if you want to even out your skin tone.<\/p>\n<h2><span id=\"When-Will-the-Benefits-or-Results-Be-Perceived\">When Will the Benefits or Results Be Perceived?<\/span><\/h2>\n<p>The effects, properties, and benefits of topical retinoic acid are seen in the medium to long term, meaning it may take between 1 and 6 months to notice results. Usually, you will begin to see that it is working after about 3 weeks; however, this depends on your tolerance and the dosage used.<\/p>\n<p>The properties are influenced by the percentage of purity as well as the usage. If it is for removing <strong>sun spots on the face<\/strong> and they are very dark, it will take longer; if they are small and light, the benefits will be much quicker. In any case, by the second month, you will likely start to see <strong>results<\/strong> in the form of <strong>clearer skin<\/strong> and a <strong>more even complexion<\/strong> on the cheeks, chin, or areas where there was different skin color.<\/p>\n<p>In the case of a retinoic acid peel, results are much faster. After performing the peel, there will usually be skin peeling, improving the tone in a few days. However, the regeneration of the epidermis will take time.<\/p>\n<p><strong>NOTE:<\/strong> It is important not to be impatient and try to rush the treatment with retinoic acid. Follow the usage instructions and do not overuse. If it is for daily application, once a day will be sufficient. If the cream contains retinol or one of its variants, you may need to use it twice in some cases, as we mentioned in the \u201c<a href=\"#Is-retinoic-acid-the-same-as-retinol\"><strong>differences between retinoic acid and retinol<\/strong><\/a>,\u201d the latter is milder.<\/p>\n<p>Do not apply the cream more times than indicated. Overuse could cause skin issues such as dermatitis, burns, and peeling. Impatience with retinoids often leads to worse problems than remedies. So use it wisely and correctly.<\/p>\n<p>If you have doubts, let\u2019s discuss how creams, serums, and gels containing retinoic acid are generally used.<\/p>\n<h2><span id=\"How-to-Use-Retinoic-Acid-Creams\">How to Use Retinoic Acid Creams<\/span><\/h2>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-97248 size-full\" src=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/how-to-use-retinoic-acid.jpg\" alt=\"How to use retinoic acid\" width=\"700\" height=\"300\" srcset=\"https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/how-to-use-retinoic-acid.jpg 700w, https:\/\/www.mismumi.com\/en\/wp-content\/uploads\/how-to-use-retinoic-acid-336x144.jpg 336w\" sizes=\"(max-width: 700px) 100vw, 700px\" title=\"\"><\/p>\n<ol>\n<li>Wash your face thoroughly with water to remove dirt and impurities.<\/li>\n<li>Dry well with a soft towel.<\/li>\n<li>Apply to the areas of the skin you want to treat.<\/li>\n<li>Repeat once a day, preferably at night.<\/li>\n<li>Use sunscreen during the day to prevent sun damage and the appearance of facial spots.<\/li>\n<\/ol>\n<p>The first time you use it, it is ideal to do a patch test on an inconspicuous area of skin. This allows you to check your tolerance to retinoic acid. This will help determine if you have any allergies to retinoic acid or any of the excipients in the cream.<\/p>\n<p>To perform a patch test with retinoids, it is best to <strong>apply a small amount<\/strong> on a tiny area of skin. Make sure it is in an area that is not visible. You can do it in a place covered by clothing, so if there is a reaction, it will be easier to hide.<\/p>\n<p>Use the cream as if it were for your face, apply it, and wait 24 hours to check the condition of the skin. If you have high sensitivity to retinoids, the area will be red and itchy. In such cases, you should use a lower concentration or find another cosmetic that serves the same purpose. This is unless it has been recommended by a dermatologist. If it has been recommended, you should always consult with them.<\/p>\n<h2><span id=\"Precautions-and-Usage-Recommendations\">Precautions and Usage Recommendations<\/span><\/h2>\n<p>Because it affects the thickness of the skin, you need to be careful with sun exposure while using it. Consider that the upper layers are removed, making your skin much more sensitive. The stratum corneum becomes thinner, and you need to use sunscreen.<\/p>\n<p>This is beneficial and is part of the effects and properties we seek, but you need to allow time for your skin to recover. If used to remove stretch marks or improve a body part, allow time as well.<\/p>\n<p>Avoid using treatments with alcohol or exfoliants at the same time, and if using perfume, be cautious as it might sting.<\/p>\n<h2><span id=\"Probable-Reactions\">Probable Reactions<\/span><\/h2>\n<p>It is common to experience a stinging sensation in the area where you applied retinoic acid or one of the other retinoids within a few minutes. This usually indicates that your sensitivity to the product is too high, and in this case, you should not use it on your face. <strong>If it is your first time using a cream with retinoic acid<\/strong>, always choose one with the lowest concentration of active substance. Once you know how it works for you, you can decide if it is suitable or if you should opt for one with a higher concentration.<\/p>\n<p>It is important to note that <strong>many people do not tolerate it well<\/strong> when used topically for acne and spots, similar to what happens with tretinoin and hydroquinone. They experience itching, peeling, and typical symptoms of dermatitis. If this is your case, you should avoid its use.<\/p>\n<p>However, do not be alarmed by using retinoic acid in a cream. The ones available are cosmetics, so there is no need to fear them, just use them with moderation and only when necessary, always following the instructions.<\/p>\n<p><strong>Retinoic acid at 0.05 and 0.025<\/strong> is just another cosmetic, but because it has <strong>skin lightening effects<\/strong> and <strong>reduces the stratum corneum<\/strong>, you need to be a bit more careful compared to exfoliants or products that aid in skin regeneration. Otherwise, use it if needed.<\/p>\n<h2><span id=\"Price-of-Retinoic-Acid\">Price of Retinoic Acid<\/span><\/h2>\n<p>This is one of its strong points. The <strong>price of retinoic acid<\/strong> is very low, making it quite affordable. Retinol and retinoids are among the cheapest cosmetic substances, so it is normal for them to be widely available compared to other cosmetic substances and acids. Some creams cost less than $10, and considering their results, they are extremely inexpensive.<\/p>\n<\/p><aside class=\"ads\"><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><!-- ah_fin_articulo --><ins class=\"adsbygoogle ah-fin-articulo\" style=\"display:inline-block\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"4055871191\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/aside><aside class=\"ads-relacionado\"><center><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><!-- mismumi_relacionado --><ins class=\"adsbygoogle\" style=\"display:block\" data-ad-format=\"autorelaxed\" data-ad-client=\"ca-pub-9582652217436894\" data-ad-slot=\"2966766890\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/center><\/aside><div class=\"clear\"><\/div>","protected":false},"excerpt":{"rendered":"<p>The retinoic acid (RA) is a derivative or metabolite of vitamin A. Well known as retinol and used in numerous anti-spot and anti-wrinkle creams or as a lotion, it also has a role in&#46;&#46;&#46;<\/p>\n","protected":false},"author":7,"featured_media":97239,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[83,84],"tags":[],"_links":{"self":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/posts\/1384"}],"collection":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/comments?post=1384"}],"version-history":[{"count":0,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/posts\/1384\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/media\/97239"}],"wp:attachment":[{"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/media?parent=1384"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/categories?post=1384"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mismumi.com\/en\/wp-json\/wp\/v2\/tags?post=1384"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}